--- title: Uncommon Knowledge image: https://magazine.clevelandclinic.org/hubfs/CC%20Magazine/Power%20of%20Everyone/Uncommon%20Knowledge/1-PHI-2212179_2022ImpactReport-story7-social.jpg --- [![POE-Logo-Mobile](https://magazine.clevelandclinic.org/hs-fs/hubfs/CC%20Magazine/Power%20of%20Everyone/Cover/POE-Logo-Mobile.png?noresize&width=224&height=38&name=POE-Logo-Mobile.png) ![POE-Logo-Desktop](https://magazine.clevelandclinic.org/hs-fs/hubfs/CC%20Magazine/Power%20of%20Everyone/Cover/POE-Logo-Desktop.png?noresize&width=552&height=65&name=POE-Logo-Desktop.png)](https://magazine.clevelandclinic.org/2022-power-of-every-one?hsLang=en) [Donate](https://give.ccf.org/CCMAG) IMPACT STORY # Uncommon Knowledge ## Share - [Share on facebook](http://www.facebook.com/share.php?u=https://magazine.clevelandclinic.org/2022-power-of-every-one/uncommon-knowledge&utm_medium=social&utm_source=facebook) - [Share on twitter](https://twitter.com/intent/tweet?original_referer=https://magazine.clevelandclinic.org/2022-power-of-every-one/uncommon-knowledge&utm_medium=social&utm_source=twitter&url=https://magazine.clevelandclinic.org/2022-power-of-every-one/uncommon-knowledge&utm_medium=social&utm_source=twitter&source=tweetbutton&text=) - [Share on linkedin](http://www.linkedin.com/shareArticle?mini=true&url=https://magazine.clevelandclinic.org/2022-power-of-every-one/uncommon-knowledge&utm_medium=social&utm_source=linkedin) - [Share on email](mailto:?subject=Check%20out%20Uncommon%20Knowledge%20&body=Check%20out%20https://magazine.clevelandclinic.org/2022-power-of-every-one/uncommon-knowledge&utm_medium=social&utm_source=email) Dr. Eric E. Roselli, whose research focuses on high-risk cardiovascular surgery, holds one of the many endowed chairs created during the centennial campaign | Photo: Annie O’Neill Over the course of The Power of Every One Centennial Campaign, 71 endowed chairs were created. One of them is held by Eric E. Roselli, MD. “At Cleveland Clinic, we commonly see uncommon things,” says Dr. Roselli, the Stephens Family Endowed Chair in Cardiothoracic Surgery. “When you see uncommon things with proximity in time, you’re better equipped to make observations that lead to discoveries for taking better care of patients.” Consider aortic arch replacement surgery. In any given year, another medical center might perform five of these complicated procedures; Cleveland Clinic performs upwards of 150, most of which entail a novel technique developed by Dr. Roselli and colleagues. Branched Stented Anastomosis Frozen Elephant Trunk Repair — B-SAFER for short — combines open-heart surgery and endovascular surgery to fix damaged blood vessels with a synthetic tube (the “elephant trunk”), fabric-covered stents and traditional suturing techniques. “It’s a complex operation because the aortic arch is where vessels to the central nervous system originate,” Dr. Roselli says. “The longer it takes, the more risk to the brain and spinal cord. We’ve modified existing devices to speed up and simplify the operation.” Investigation toward commercialization of new dedicated B-SAFER technology is in the works. **In the meantime, a B-SAFER clinical trial is underway, supported with funding from the Stephens family. The generosity of donors also allows Dr. Roselli to train future physician-scientists in his translational research lab focused on high-risk cardiovascular surgery.** Here, where the uncommon is common, philanthropy is a common thread weaving progress through care, research and education. “Across our mission,” Dr. Roselli says, “we’re using philanthropy to drive innovation.” ## In this Report ### [![Female lab technician wearing a mask, gloves, and white lab coat administers a sample in a medical lab.](https://magazine.clevelandclinic.org/hs-fs/hubfs/CC%20Magazine/Power%20of%20Everyone/How%20to%20Change%20the%20World/Howtochangetheworld-small.jpg?width=242&height=214&name=Howtochangetheworld-small.jpg) IMPACT STORY How to Change the World](https://magazine.clevelandclinic.org/2022-power-of-every-one/how-to-change-the-world?hsLang=en) ### [![Dr. Michaela Gack stands on the right and Dr. Lucky Sarkar stands on the left, both wearing lab coats, goggles, masks, and gloves, observe objects in a research lab.](https://magazine.clevelandclinic.org/hs-fs/hubfs/CC%20Magazine/Power%20of%20Everyone/Going%20Antiviral/1-PHI-2212179_2022ImpactReport-story6-small.jpg?width=242&height=214&name=1-PHI-2212179_2022ImpactReport-story6-small.jpg) IMPACT STORY Going Antiviral](https://magazine.clevelandclinic.org/2022-power-of-every-one/going-antiviral?hsLang=en) ### [![Black and blue illustration of donors for Power for Everyone Issue](https://magazine.clevelandclinic.org/hs-fs/hubfs/CC%20Magazine/Power%20of%20Everyone/Donor%20Spotlight/Donors_small.jpg?width=242&height=214&name=Donors_small.jpg) SPOTLIGHT The Power of Every Donor](https://magazine.clevelandclinic.org/2022-power-of-every-one/the-power-of-every-donor?hsLang=en) ### [![neon yellow circles of varying sizes with a black background](https://magazine.clevelandclinic.org/hs-fs/hubfs/CC%20Magazine/Power%20of%20Everyone/Every%20Where%20DV02/DV02-Sm.jpg?width=242&height=214&name=DV02-Sm.jpg) DATA VIZ 2 Every Where](https://magazine.clevelandclinic.org/2022-power-of-every-one/every-where?hsLang=en) - [Contact](https://magazine.clevelandclinic.org/2022-power-of-every-one/contact?hsLang=en) [Donate](https://give.ccf.org/CCMAG) [![Cleveland Clinic](https://magazine.clevelandclinic.org/hs-fs/hubfs/CC%20Magazine%20Template%20Assets/img/logo-cc.png?width=300&name=logo-cc.png "Cleveland Clinic")](https://my.clevelandclinic.org/) © 2026 Cleveland Clinic. 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