THE 1950s
A Real Heart-Stopper
![black and white image of multiple doctors in a surgery wearing surgical scruba](https://magazine.clevelandclinic.org/hs-fs/hubfs/CC%20Magazine/Centennial/1950s/A%20Real%20Heart%20Stopper/Centennial-RealHeartStopper-Wide.jpg?width=1030&height=540&name=Centennial-RealHeartStopper-Wide.jpg)
Photo: Cleveland State University Michael Schwartz Library Special Collections
In 1956, Cleveland Clinic performed a groundbreaking operation that established stopped-heart surgery as a regular practice. A team led by Donald Effler, MD, and Laurence Groves, MD, connected the patient — a 17-month-old boy with a ventricular septal defect — to a heart-lung machine designed by Willem Kolff, MD, PhD. Once the machine was pumping blood and oxygen, a dose of potassium citrate temporarily paralyzed the heart. “With a dry, quiet, clearly visible field in which to work, we believe that a new era of heart surgery has opened,” Dr. Effler said. According to news accounts, the patient was “up and about” soon afterward.